A METHOD AND SYSTEM FOR MONITORING HORIZONTAL GENE TRANSFER IN LIVING AND FIXED CELLS, AND USES THEREOF
DEINOVE,

 

on



Highlight Terms
The method and the system of the invention comprise selective detection of the DNA transferred from one cell to another, while substantially always being blind to the DNA from either donor or recipient cell. The detection is effected by means of at least one probe binding specifically to the DNA horizontally transferred from a wild-type DNA methylation-proficient cell to a DNA methylation-deficient cell. The invention can be used in any of the forms of bacterial sex, including direct transformation by DNA, bacteriophage-mediated transduction or conjugation mating between two bacterial partners.
  • WO2008IB02141